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Diabetes drug might hike heart risk

A popular prescription drug for type 2, or adult-onset, diabetes increases a person's risk of heart attack, an analysis of 42 clinical trials suggests.

The drug, called rosiglitazone or Avandia, is taken to lower blood sugar. The Food and Drug Administration approved the drug in 1999, and more than 11 million prescriptions were filled for it last year in the United States.

In the new analysis, researchers tabulated heart attacks among 15,560 people with diabetes who got rosiglitazone in various trials and 12,283 people who also had diabetes but didn't receive the drug.

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