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Shared recipes for longer life

Study homes in on proteins that may affect longevity

By
11:51am, July 7, 2008

Eating a calorie-restricted diet and being female are the best bets for living longer, at least for animals. Now scientists have discovered that some links may exist between the two.

Women live about five years longer on average than men, and a similar longevity advantage exists for other mammal species, including rats. Numerous experiments have also shown that eating a nutritionally complete diet relatively low in calories can also extend lifespan: A daily calorie decrease of 30 percent correlates to living 30 to 50 percent longer than normal for all animal species tested thus far, including mice and dogs.

To find out whether these two scenarios for longer life share common molecular mechanisms, Adamo Valle of University of the Balearic Islands in Spain and his colleagues compared male and female rats. Each gender group was separated into two groups, one fed a normal diet and the other fed a calorie-restricted

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