New strains of lab animals bred to better pinpoint the genetic roots of disease
Scientists have built a better mouse. But rest easy — these mice don’t require improved traps.
The new mice may give scientists an advantage in tracing genetic sources of common diseases and investigating interactions between genes and environmental factors. In a series of 15 papers published in the February issues of Genetics and G3: Genes, Genomes, Genetics, researchers describe the creation of the new-and-improved mice, known as the Collaborative Cross strains, and some of the ways scientists may use the mice in medical studies.
Biomedical researchers use inbred strains of