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Antibiotics linked to fat buildup

Drugs might impact body composition, weight by altering mix of gut microbes

Antibiotics may plump up cows, pigs, chickens, mice and humans alike, new research suggests.

For decades, low doses of antibiotics have been given to livestock to make the animals grow and bulk up faster, but no one really knew how the drugs promoted growth. Now, researchers led by microbiologist Martin Blaser at the New York University School of Medicine report online August 22 in Nature that antibiotics alter the mix of bacteria in the intestines of mice and cause the rodents to build up more fat than normal.

In a separate study, published online August 21 in the International Journal of Obesity, Blaser’s group found a link between antibiotic use in babies younger than 6 months old and being overweight at age 3. Together, the studies suggest that medications that alter the mix of friendly bacteria in the gut may have lasting effects on body weight.

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