Feature

The Cancer of Dorian Gray

Is growing old an inescapable cost of averting malignancy?

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11:32am, October 30, 2006

Dorian Gray, the everlasting dandy of Oscar Wilde's novel, halted aging. Rather than his body growing old, his portrait suffered the insults of time. In recent years, biologists have created real-life Dorian Grays: mice that don't show certain signs of age. But in both the story and the lab, there were trade-offs. By remaining young, the fictional Dorian Gray became self-destructive. In the scientific plotline, the specially bred mice develop cancer and die young.

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