Latest Issue of Science News


It’s enough to give you heartburn

Wonder drugs they may be, but PPIs are overprescribed and pose some health risks

In the arms race against heartburn, one class of drug outperforms the competition by going straight to the source. The proton pump inhibitors, PPIs for short, block acid manufacture at the subcellular level. In contrast, acid reflux drugs such as Tums and Maalox neutralize the acid. Others, like Zantac and Tagamet, slow down its production by blocking the histamine 2-receptor. PPIs do require a day or two to start suppressing the symptoms of acid reflux. But once PPIs kick in, they put out the fire with stunning efficiency.

Note: To comment, Science News subscribing members must now establish a separate login relationship with Disqus. Click the Disqus icon below, enter your e-mail and click “forgot password” to reset your password. You may also log into Disqus using Facebook, Twitter or Google.

This article is available only to subscribing members. Join SSP today or Log in.