Depression gene search disappoints

Comprehensive effort to find DNA links to low mood comes up empty

By Laura Sanders, 10:22 AM January 16, 2013

A massive effort to uncover genes involved in depression has largely failed. By combing through the DNA of 34,549 volunteers, an international team of 86 scientists hoped to uncover genetic influences that affect a person’s vulnerability to depression. But the analysis turned up nothing.

The results are the latest in a string of large studies that have failed to pinpoint genetic culprits of depression. “I’m disappointed,” says study coauthor Henning Tiemeier of Erasmus Medical Center in Ro...

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