Lab-grown heart has rhythm

Researchers transform stem cells into contracting cardiac cells

By Jessica Shugart, 10:41 AM August 15, 2013

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Transformed from a sample of human skin, lab-grown heart muscle cells contract spontaneously in a dish (shown). To create the heart cells, Lei Yang at the University of Pittsburgh and colleagues first converted skin cells into stem cells and then dosed the cells with a tailor-made concoction of growth factors.

The researchers then added the resulting cardiac muscle cells to the structural shell of a mouse heart that had been stripped of its own cells. The human cells transformed...

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