Gut-brain communication failure may spur overeating

Restoring a depleted molecule in obese mice repaired their abnormal response to food

By Cristy Gelling, 12:55 PM August 15, 2013

Repairing a faulty communication line between the gut and the brain can quell the urge to overeat, an experiment that cured chubby mice of their junk food addiction indicates. A similar strategy might be used to treat compulsive eating in people.

Some scientists have proposed that, in both mice and humans, overeating can resemble drug addiction; the more food a person consumes, the less responsive the brain becomes to the pleasure of eating. By restoring normal communication between the gut an...

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