Cancer variants found in ‘neglected’ region of genome
Mutations outside of genes associated with disease
By Tina Hesman Saey, 14:39 PM October 3, 2013
Parts of human DNA that do not contain genes but instead turn them on and off may be just as vulnerable to cancer-causing mutations as protein-producing genes are, a new study finds.
Using computer programs to comb through the DNA of 88 cancer patients, researchers identified 98 mutations in gene-regulating parts of the genome that may be causing the patients’ breast, prostate or brain tumors, the team reports in the Oct. 4 Science.
The findings may help researchers better understand which gene...
Source URL: https://www.sciencenews.org/article/cancer-variants-found-‘neglected’-region-genome?mode=magazine&context=187439