Gene that boosts Alzheimer’s risk might protect against it too

A new study puts different APOE types into mice to find new treatments for the disease

By Bethany Brookshire, 15:42 PM November 21, 2013

Carrying a specific version of the apolipoprotein E, or APOE, gene is one of the most important genetic risk factors for late-onset Alzheimer’s disease. But another form of the gene is not a risk factor. What is the difference? How do the proteins made by these genes, which normally transport cholesterol, affect Alzheimer’s? And if we find out, can we use them to fight the disease?

Eloise Hudry and a group of scientists at Harvard Medical School set out to understand how different versions of ...

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