Gene adds wrinkle to brain development
Mutation results in misshapen folds tied to intellectual disabilities
By Laura Sanders, 12:10 PM February 13, 2014
Some of the human brain’s wrinkles are forged by the behavior of a single gene, scientists report in the Feb. 14 Science.
By scanning more than 1,000 people’s brains, researchers identified five with malformed wrinkles in a specific region. The abnormalities — numerous shallow dips surrounding an unusually wide brain furrow called the Sylvian fissure — were linked with intellectual and language disabilities and seizures in these people.
All five people had mutations that dampened the behavior o...
Source URL: https://www.sciencenews.org/article/gene-adds-wrinkle-brain-development