Bank voles provide clue to prion disease susceptibility

Bank voles provide clue to prion disease susceptibility

Mice engineered with vole protein suffer disorders that don’t usually infect them

By Tina Hesman Saey, 09:26 AM April 4, 2014

Prion diseases, the frightening neuron-killing disorders that transmit via infectious proteins rather than by viruses or bacteria, rarely jump from one species to another. But just a few amino acids can tear down the barriers that stop one animal from contracting another species’ prion disease.

Bank voles are particularly susceptible to the infectious brain-wasting diseases. That susceptibility stems from the structure of one of the vole’s brain proteins, researchers from the University of Cal...

Source URL: https://www.sciencenews.org/article/bank-voles-provide-clue-prion-disease-susceptibility?mode=magazine&context=188379