Enzyme may help aspirin protect against colon cancer

People with low levels don’t benefit from common drug

By Nathan Seppa, 13:58 PM April 23, 2014

Aspirin, the pain reliever that lowers fever and inhibits blood clotting, also shows impressive but spotty protection against colorectal cancer. A new study reveals that people who fail to get this benefit from the drug might be making too little of a key enzyme in the colon.

Among aspirin users, those with ample levels of the enzyme 15-PGDH are about half as likely to develop colon cancer as those with low levels of 15-PGDH. Scientists who analyzed data from two studies spanning up to three d...

Source URL: https://www.sciencenews.org/article/enzyme-may-help-aspirin-protect-against-colon-cancer