Bone marrow transplant could reverse sickle cell in adults

Relatively mild treatment works for most patients in small study

By Nathan Seppa, 17:10 PM July 1, 2014

Sickle cell disease in adults might be treatable with a bone marrow transplant, researchers report July 1 in JAMA.

Hundreds of children with sickle cell disease had previously been treated and most cured with the procedure, which requires that their defective bone marrow be largely wiped out by radiation and chemotherapy and then replaced by a closely matched marrow transplant. Until recently, the harsh regimen was considered too risky for adults because they often have accumulated organ damag...

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