New view reveals how DNA fits into cell

Map of 3-D structure of the entire human genome shows fractal folding is key

By Laura Sanders, 11:11 AM October 8, 2009

Cells are tidy packers, cramming DNA into nuclei to create a tangle-free, dense ball with pieces that are still accessible, researchers report October 9 in Science. The findings, based on a new three-dimensional view of the whole human genome, solve a long-standing biological mystery and may lead to a deeper understanding of how genes operate. 

Except during division, a human cell’s two meters of DNA is jammed into an area about a hundredth of a millimeter wide. But researchers had been pu...

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