Early disruption of schizophrenia gene causes problems later

Mouse study may help researchers understand how disease develops

By Laura Sanders, 17:42 PM February 22, 2010

SAN DIEGO — Disrupting a gene implicated in schizophrenia early in development leads to brain anomalies and behavioral defects later in life, a new study in mice finds. The results, presented February 22 at the annual meeting of the American Association for the Advancement of Science, may help researchers understand how early developmental problems contribute to schizophrenia — a disease that typically shows up after adolescence.

In humans, mutations in a gene called DISC1 cause flaws in n...

Source URL: https://www.sciencenews.org/article/early-disruption-schizophrenia-gene-causes-problems-later