Mom's past drug abuse may alter brain chemistry of offspring

Study in rats shows lingering effects of adolescent opiate use may be passed on for two generations

By Tom Siegfried, 17:42 PM November 14, 2010

SAN DIEGO — Drug-using moms-to-be who quit before pregnancy starts can still raise the risk among both their children and grandchildren for addiction or other psychiatric disorders, a new study in rats suggests.

Researchers at the Tufts University Cummings School of Veterinary Medicine in North Grafton, Mass., exposed female rats to morphine for 10 days during adolescence. After three weeks drug-free, the rats mated with healthy males. Male offspring of those matings produced less of...

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