Body attacks lab-made stem cells

Body attacks lab-made stem cells

In mice, the immune system targets and destroys reprogrammed adult skin cells

By Tina Hesman Saey, 13:06 PM May 13, 2011

Stem cells created in the lab by reprogramming adult cells from a patient’s own body can come under attack from the immune system, a new study in mice suggests.

The finding may present a major barrier to using reprogrammed stem cells, called induced pluripotent stem cells or iPS cells, in treatments to repair or replace damaged tissues.

The study introduces a needed note of caution into what had become a headlong race to rush reprogrammed cells into clinical use, says Chad Tang, a stem c...

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