Ketamine's antidepressant effect explained

Potential fast-acting treatment boosts BDNF

By Laura Sanders, 15:19 PM June 14, 2011

The anesthetic ketamine works against depression by quickly boosting levels of a brain compound that has been linked to the condition, a new study in mice shows. The research may lead to highly effective and fast-acting antidepressants that provide relief within hours instead of weeks, scientists report online June 15 in Nature.

Traditional antidepressants can be effective but often take weeks or months to improve symptoms. “You can control malignant hypertension within minutes; a bad incre...

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