Chemo drug drives growth of some tumors

Ovarian cancer stem cells stimulated by common treatment

By Tina Hesman Saey, 17:28 PM January 23, 2012

Chemotherapy drugs designed to kill tumors may actually encourage ovarian cancer by stimulating the growth of cells that give rise to the malignancy, a new study finds.

“It was quite a surprise, actually, that chemotherapy could stimulate growth,” says Kenneth Nephew, a cancer biologist at the Indiana University School of Medicine in Bloomington, who was not involved in the new work. “When clinicians see this paper it may raise a few eyebrows.”

Researchers led by Patricia Donahoe and Xiaol...

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