Stem cell treatment spurs cartilage growth

Stem cell treatment spurs cartilage growth

Compound prompts manufacture of lost connective tissue in mice

By Nathan Seppa, 16:37 PM April 4, 2012

A small molecule dubbed kartogenin encourages stem cells to take on the characteristics of cells that make cartilage, a new study shows. And treatment with kartogenin allowed many mice with arthritis-like cartilage damage in a knee to regain the ability to use the joint without pain.

The findings provide new clues in the long-running effort to find ways to regenerate cartilage, a central puzzle in the battle against osteoarthritis, scientists report online April 5 in Science.

The new appro...

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