Like a prion, Alzheimer's protein seeds itself in the brain
Misshapen amyloid-beta self-propagates in mice
By Laura Sanders, 09:40 AM June 19, 2012
The Alzheimer’s-related protein amyloid-beta is an infectious instigator in the brain, gradually contorting its harmless brethren into dangerous versions, new evidence suggests. The study adds to the argument that A-beta is a prion, a misfolded protein that behaves like the contagious culprits behind Creutzfeldt-Jakob disease in people, scrapie in sheep and mad cow disease.
There’s no evidence that Alzheimer’s can spread from person to person, but thinking of Alzheimer’s as a prion disease ...
Source URL: https://www.sciencenews.org/article/prion-alzheimers-protein-seeds-itself-brain