Genetic mutations may explain a brain cancer’s tenacity
DNA damage to adult cells implicated in glioblastoma
By Tina Hesman Saey, 12:17 PM October 18, 2012
New work could help explain why a deadly type of brain cancer recurs easily even after surgery, radiation and chemotherapy have apparently banished it. Fully developed brain cells, not just stem cells, may take on new identities to evade therapy and come back later, the study suggests.
Just two changes to cancer-related genes in some adult brain cells are enough to spur the genesis of glioblastomas, Inder Verma, a molecular biologist at the Salk Institute for Biological Studies in La Jolla, Ca...
Source URL: https://www.sciencenews.org/article/genetic-mutations-may-explain-brain-cancer’s-tenacity