Cloning-like method targets mitochondrial diseases

Cloning-like method targets mitochondrial diseases

Providing healthy ‘power plants’ in donor eggs appears feasible in humans

By Tina Hesman Saey, 14:18 PM October 24, 2012

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A technique that puts one woman’s nuclear DNA into another woman’s donor egg cell may be feasible for correcting inherited diseases caused by faulty cellular power sources. The technique has already produced healthy baby rhesus monkeys, and now it raises the possibility of preventing mitochondrial diseases in thousands of people each year.

Mitochondria, energy-producing organelles inside cells, carry circles of DNA important for the power plants’ function. Mutations of the mitoc...

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