Disrupted brain chatter produces schizophrenia-like symptoms in mice

By quieting part of the thalamus, researchers create rodents with cognitive deficits

By Meghan Rosen, 14:55 PM March 20, 2013

Shushing neural chitchat in mouse brains can spark schizophrenia-like symptoms, a new study suggests. The findings are the first to demonstrate — at least in mice — that curbing communication among neurons in certain parts of the brain can cause some of the cognitive problems associated with schizophrenia.

By muzzling neurons in the mediodorsal thalamus, or MD — a cell cluster that sends signals to the brain’s outer layer — researchers hindered mouse memory and learning in much the same way...

Source URL: https://www.sciencenews.org/article/disrupted-brain-chatter-produces-schizophrenia-symptoms-mice