Eye drops reduce signs of macular degeneration in mice

Eye drops reduce signs of macular degeneration in mice

Targeting cholesterol in retina stops rogue blood vessel growth often seen in the vision disease

By Tina Hesman Saey, 14:20 PM April 1, 2013

Cholesterol-lowering eye drops may one day help preserve sight in people with a common cause of age-related vision loss, a new study suggests.

In old mice, eye drops that stimulate cells to shed cholesterol rejuvenated immune cells to fight off blood vessels encroaching into the retina, a hallmark of advanced age-related macular degeneration. The finding suggests that cholesterol buildup in the eye helps promote the condition, a leading cause of vision loss in people 50 and older.

Macular...

Source URL: https://www.sciencenews.org/article/eye-drops-reduce-signs-macular-degeneration-mice?mode=magazine&context=4551