Ovarian cancer drug candidate passes early clinical test

Experimental medicine uses seek-and-destroy technique against tumor cells

By Nathan Seppa, 15:11 PM April 8, 2013

WASHINGTON — A newfangled drug candidate featuring an antibody that totes a tumor-killing toxin can knock down ovarian cancer in some patients. In the first test of the experimental drug in people, scientists gave it to 44 patients with advanced ovarian cancer that was resistant to the effects of platinum-based chemotherapy, a standard treatment.

One patient showed what the researchers called a “complete response,” meaning any tumors became undetectable. Four other patients had a partial r...

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