Bacterial molecules may prevent inflammatory bowel disease

Common compounds produced by gut microbes quench colitis in mice

By Jessica Shugart, 12:35 PM July 9, 2013

Common molecules made by bacteria in the gut may act as chill pills for the immune system. Molecules secreted by intestinal bacteria work to prevent misplaced immune attacks in inflammatory bowel diseases like colitis, a new study finds.

“It is a huge advance,” says Sarkis Mazmanian of Caltech. “This opens up the notion that a very easy and potentially very safe therapy for inflammatory bowel disease could exist.”

Decades of research have hinted that microbes play a role in immune-related ...

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