Fructose may be key to weight gain

Mice that could not make or metabolize the sugar gained less than normal mice

By Nathan Seppa, 17:36 PM September 9, 2013

Mice lacking the ability to metabolize fructose don’t gain nearly as much weight as normal mice do, researchers report September 10 in Nature Communications.

Fructose, which some people blame for the obesity epidemic and its related health crises (SN: 6/1/13, p. 22), shows up in high-fructose corn syrup and in table sugar, or sucrose. The body also makes home-grown fructose by modifying glucose in a process involving an enzyme called aldose reductase.

Richard Johnson of the University of Color...

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