Of Mice and Man

The lab mouse is being remodeled to better mimic how humans respond to disease

By Susan Gaidos, 10:45 AM March 7, 2013

It looked like a lost cause: a 61-year-old patient with advanced pancreatic cancer — one of the deadliest diagnoses. Ordinarily, doctors wouldn’t have much choice. They could try chemotherapy drugs one at a time to see if any worked, or they could slam the tumor with a cocktail of chemicals that had shown some success with similar cases.

But this time the doctors had another option: trying out potential treatments on mice. These weren’t run-of-the-mill lab rodents, though. Scientists had cr...

Source URL: https://www.sciencenews.org/article/mice-and-man?mode=magazine&context=4548