Engineered salivary glands keep juices flowing

Organs grown in a lab dish do their job when transplanted into mice

By Jessica Shugart, 11:01 AM October 1, 2013

Salivary glands engineered in the lab wet the mouths of mice after transplantation, researchers report October 1 in Nature Communications.

Takashi Tsuji of the Tokyo University of Science in Noda, Japan and colleagues extracted clusters of immature cells from mouse embryos and grew nascent salivary glands in a gel-like substance for three days. Then the researchers implanted the incipient organs in mice that had had salivary glands removed. The engineered glands took up residence in the mice a...

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