All mice are the same, until they're not

‘Identical’ Black 6 substrains show gene-linked differences in response to cocaine

By Bethany Brookshire, 18:51 PM January 2, 2014

When most people think of the quintessential lab mouse, they think of a little white mouse with red eyes. Soft fur. A timid nature. But scientists think of something very different. This mouse is black, small and fast, with pink ears and a pinkish tail. It’s got black eyes to match. The fur may be soft, but the temper sure isn’t. This is the C57 Black 6 mouse.

Each Black 6 mouse should be almost identical to every other Black 6 mouse. They have been bred to their own siblings for hundreds of g...

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