Hormone hampers effects of marijuana

Study in rodents could lead to new treatments for cannabis addiction

By Laura Sanders, 13:54 PM January 6, 2014

A nondescript hormone that moonlights as a potent pot blocker in the brain may lead to drugs that help people curb cannabis dependence. The hormone pregnenolone blunts marijuana’s effects in rats and mice, scientists report in the Jan. 3 Science.

The results are “incredibly exciting, both at a scientific level and at the level of public health,” says Margaret Haney of Columbia University Medical Center. Recent laws that legalize medical marijuana will expand the already-popular drug’s reach, l...

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