Experimental drug might get the salt out

Rats could eat a salty diet without sodium levels rising

By Nathan Seppa, 16:44 PM March 12, 2014

By keeping sodium out of circulation, an experimental drug might protect against high blood pressure and possibly heart failure, both of which are linked to a high-salt diet. Researchers report that the candidate drug can usher a good portion of sodium out of the body before it reaches the bloodstream and the kidneys.


A salty diet can tilt the sodium balance in the blood and hamper kidney function. The experimental drug, called tenapanor, can block sodium from passing through membranes of the...

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