Small molecule makes brain cancer cells collapse and die

By Ashley Yeager, 13:05 PM March 20, 2014

Damaged cells that cause the most aggressive type of brain cancer collapse and die when exposed to the molecule Vacquinol-1.

The molecule makes the glioblastoma tumor cells draw in material from outside its walls into bags called vacoules. Bringing in a lot of these bags causes the cells' outer walls to collapse, which kills the cells. In mice with this type of brain tumor, Vacquinol-1 forced the collapse of only the tumor cells. Brain cells, neurons and other types of cancer cells did not res...

Source URL: https://www.sciencenews.org/blog/science-ticker/small-molecule-makes-brain-cancer-cells-collapse-and-die