Unsolved drugs

Unsolved drugs

A simmering controversy surrounds what’s still unknown about how antibiotics kill

By Beth Mole, 10:03 AM April 17, 2014

Penicillin attacks with a calculated strike, splitting open cell walls. Kanamycin sends a bacterium’s protein assembly line into mayhem. Ciprofloxacin dices a microbe’s DNA into a genetic hash. Like trained snipers, each of these common antibiotics seems to dispatch bacteria with a simple tactic: Target a high-profile molecule crucial to survival and, with a single, clean shot, defeat the whole cell.

For decades, this notion of how antibiotics kill has guided the design and deployment of drugs...

Source URL: https://www.sciencenews.org/article/unsolved-drugs