Putting BPA-based dental fillings in perspective

Small effects could have a big social impact, but mechanisms of any bis-GMA neurotoxicity remain elusive

By Janet Raloff, 18:00 PM July 16, 2012

A new study finds that children who have their cavities filled with a white composite resin known as bis-GMA appear to develop small but quantifiable drops in psychosocial function. To put it simply: Treated kids can become more moody, aggressive and generally less well adjusted.

Bis-GMA is hardly a household name, although its starting ingredient — bisphenol A — is. An estrogen-mimicking compound, BPA is best known as a building block of some clear plastics, food-contact resins and inks us...

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