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  • gene-edited cancer cells
  • HPV
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Your search has returned 119 articles:
  • News

    Cancer cells engineered with CRISPR slay their own kin

    Using gene editing, scientists have hoodwinked tumor cells into turning against their own kind.

    Cancer cells circulating in the bloodstream have something of a homing instinct, able to find and return to the tumor where they originated. To capitalize on that ability, researchers engineered these roving tumor cells to secrete a protein that triggers a death switch in resident tumor cells...

    07/11/2018 - 14:00 Cancer, Biomedicine, Genetics
  • News

    Evidence grows that an HPV screen beats a Pap test at preventing cancer

    Evidence continues to grow that screening for human papillomavirus infection bests a Pap test when it comes to catching early signs of cervical cancer.

    In a large clinical trial of Canadian women, pap tests more often missed warning signs of abnormal cell growth in the cervix than did HPV tests, researchers report July 3 in JAMA.  As a result, at the end of a four-year period,...

    07/03/2018 - 11:58 Health, Clinical Trials, Cancer
  • Feature

    How to make CAR-T cell therapies for cancer safer and more effective

    This wasn’t 15-year-old Connor McMahon’s first time in the hospital. But the 107° fever he’d been running for three days had his dad frightened. The teen was hallucinating, talking gibberish and spouting curses.

    “I thought he was going to die,” says Connor’s father, Don McMahon, who stayed close as his son received and recovered from an experimental treatment for leukemia. “It was really...

    06/27/2018 - 09:00 Cancer, Health, Clinical Trials
  • Editor's Note

    Medical breakthroughs come with a human cost

    Medical innovations can be risky, as this issue’s cover story on new CAR-T cell therapies for cancer reveals. The treatments, which tailor a patient’s own immune system cells to attack cancer, can be astonishingly successful. But CAR-T therapy can also be an untamed beast, unleashing a ferocious immune response that indiscriminately attacks the body. The challenge scientists face now...
    06/27/2018 - 07:00 Health, Cancer, History of Science
  • News

    Poliovirus treatment helped patients with deadly brain tumors live longer

    Few treatment options are available to people facing a second battle with a particularly fatal type of brain tumor called glioblastoma. But dosing the tumor with a genetically modified poliovirus — one that doesn’t cause the eponymous, devastating disease — may give these patients more time, a small clinical study suggests.

    Of 61 people with recurring glioblastoma who were treated with...

    06/26/2018 - 17:50 Cancer, Clinical Trials
  • News in Brief

    Experts advise: Start colorectal screening at 45, not 50

    Colorectal cancer screening should begin at age 45 rather than 50, according to new guidelines released May 30 by the American Cancer Society. The recommendation is a response to the steady rise over decades in the colorectal cancer rate in younger Americans (SN: 4/1/17, p. 5).

    For people at average risk for colorectal cancer — those without a personal or family history of the disease...

    05/31/2018 - 10:50 Health, Cancer
  • 50 years ago, starving tumors of oxygen proposed as weapon in cancer fight

    Starve the tumor, not the cell

    Animal experiments demonstrate for the first time that transplanted tumors release a chemical into the host’s bloodstream that causes the host to produce blood vessels to supply the tumor.… If such a factor can be identified in human cancers … it might be possible to prevent the vascularization of tumors. Since tumors above a certain small size require...

    05/04/2018 - 11:00 Cancer, Biomedicine, Cells
  • News

    An enzyme involved in cancer and aging gets a close-up

    Like a genetic handyman, an elusive enzyme deep inside certain cells repairs the tips of chromosomes, which fray as cells divide. It’s prized by rapidly dividing cells – like stem cells and tumor cells – and by scientists on the hunt for cancer and other disease therapies.

    Now researchers have the best picture yet of this enzyme, called telomerase. Using cryo-electron microscopy,...

    05/04/2018 - 10:00 Health, Cells, Cancer
  • News

    The science behind cancer warnings on coffee is murky at best

    Californians will soon be taking their coffee with cream and a cancer warning, after a court ruled that the state’s retailers must label coffee as containing a carcinogen. The decision followed an eight-year legal battle, which boiled down to a question that has plagued coffee drinkers and scientists alike: Is drinking coffee healthy, or not?

    The judge’s ruling, issued Wednesday, says...

    03/30/2018 - 17:23 Cancer
  • News

    Human skin bacteria have cancer-fighting powers

    Certain skin-dwelling microbes may be anticancer superheroes, reining in uncontrolled cell growth. This surprise discovery could one day lead to drugs that treat or maybe even prevent skin cancer.

    The bacteria’s secret weapon is a chemical compound that stops DNA formation in its tracks. Mice slathered with one strain of Staphylococcus epidermidis that makes the compound developed fewer...

    02/28/2018 - 15:49 Health, Cancer, Microbiology