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E.g., 10/19/2018
E.g., 10/19/2018
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  • James Allison and Tasuku Honjo
  • T cell
  • lab testing
Your search has returned 122 articles:
  • News

    Discovery of how to prod a patient’s immune system to fight cancer wins a Nobel

    Stopping cancer by removing brakes on the immune system has earned James P. Allison of the University of Texas MD Anderson Cancer Center in Houston and Tasuku Honjo of Kyoto University in Japan the Nobel Prize in physiology or medicine.

    “Allison’s and Honjo’s discoveries have added a new pillar in cancer therapy,” Nobel committee member Klas Kärre said in an Oct. 1 news conference...

    10/01/2018 - 14:30 Cancer, Physiology
  • Science Ticker

    Cancer immunotherapy wins the 2018 medicine Nobel Prize

    James P. Allison of MD Anderson Cancer Center in Houston and Tasuku Honjo of Kyoto University in Japan have won the Nobel Prize in physiology or medicine for advances in harnessing the immune system to fight cancer.

    All previous types of cancer therapy were directed at the tumor cell, but Allison’s and Honjo’s approach was to remove brakes that keep the immune system in check, unleashing...

    10/01/2018 - 06:42 Physiology, Cancer
  • Science Ticker

    There’s a new cervical cancer screening option

    For cervical cancer screening, there’s a new option in town.

    Women ages 30 to 65 can opt to have human papillomavirus, or HPV, testing alone every five years, according to new recommendations from the U.S. Preventive Services Task Force.

    HPV testing alone joins two other alternatives that are still endorsed: an HPV test plus a Pap test every five years, or a Pap test alone every...

    08/21/2018 - 11:00 Health, Cancer
  • News

    Cancer cells engineered with CRISPR slay their own kin

    Using gene editing, scientists have hoodwinked tumor cells into turning against their own kind.

    Cancer cells circulating in the bloodstream have something of a homing instinct, able to find and return to the tumor where they originated. To capitalize on that ability, researchers engineered these roving tumor cells to secrete a protein that triggers a death switch in resident tumor cells...

    07/11/2018 - 14:00 Cancer, Biomedicine, Genetics
  • News

    Evidence grows that an HPV screen beats a Pap test at preventing cancer

    Evidence continues to grow that screening for human papillomavirus infection bests a Pap test when it comes to catching early signs of cervical cancer.

    In a large clinical trial of Canadian women, pap tests more often missed warning signs of abnormal cell growth in the cervix than did HPV tests, researchers report July 3 in JAMA.  As a result, at the end of a four-year period,...

    07/03/2018 - 11:58 Health, Clinical Trials, Cancer
  • Feature

    How to make CAR-T cell therapies for cancer safer and more effective

    This wasn’t 15-year-old Connor McMahon’s first time in the hospital. But the 107° fever he’d been running for three days had his dad frightened. The teen was hallucinating, talking gibberish and spouting curses.

    “I thought he was going to die,” says Connor’s father, Don McMahon, who stayed close as his son received and recovered from an experimental treatment for leukemia. “It was really...

    06/27/2018 - 09:00 Cancer, Health, Clinical Trials
  • Editor's Note

    Medical breakthroughs come with a human cost

    Medical innovations can be risky, as this issue’s cover story on new CAR-T cell therapies for cancer reveals. The treatments, which tailor a patient’s own immune system cells to attack cancer, can be astonishingly successful. But CAR-T therapy can also be an untamed beast, unleashing a ferocious immune response that indiscriminately attacks the body. The challenge scientists face now...
    06/27/2018 - 07:00 Health, Cancer, History of Science
  • News

    Poliovirus treatment helped patients with deadly brain tumors live longer

    Few treatment options are available to people facing a second battle with a particularly fatal type of brain tumor called glioblastoma. But dosing the tumor with a genetically modified poliovirus — one that doesn’t cause the eponymous, devastating disease — may give these patients more time, a small clinical study suggests.

    Of 61 people with recurring glioblastoma who were treated with...

    06/26/2018 - 17:50 Cancer, Clinical Trials
  • News in Brief

    Experts advise: Start colorectal screening at 45, not 50

    Colorectal cancer screening should begin at age 45 rather than 50, according to new guidelines released May 30 by the American Cancer Society. The recommendation is a response to the steady rise over decades in the colorectal cancer rate in younger Americans (SN: 4/1/17, p. 5).

    For people at average risk for colorectal cancer — those without a personal or family history of the disease...

    05/31/2018 - 10:50 Health, Cancer
  • 50 years ago, starving tumors of oxygen proposed as weapon in cancer fight

    Starve the tumor, not the cell

    Animal experiments demonstrate for the first time that transplanted tumors release a chemical into the host’s bloodstream that causes the host to produce blood vessels to supply the tumor.… If such a factor can be identified in human cancers … it might be possible to prevent the vascularization of tumors. Since tumors above a certain small size require...

    05/04/2018 - 11:00 Cancer, Biomedicine, Cells