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  • Science Ticker

    Ebola vaccine proves effective, final trial results show

    An experimental Ebola vaccine has triumphed in West Africa.

    Of 5,837 people in Guinea who received a single shot of the vaccine, rVSV-ZEBOV, in the shoulder, none became infected with the virus 10 to 84 days after vaccination. That’s “100% protection,” researchers report December 22 in the Lancet.

    World Health Organization researcher Ana Maria Henao-Restrepo and colleagues tested...

    12/22/2016 - 18:30 Clinical Trials, Health
  • News in Brief

    Ebola vaccine proves effective

    An experimental Ebola vaccine has triumphed in West Africa.

    Of 5,837 people in Guinea and Sierra Leone who received a single shot of the vaccine, rVSV-ZEBOV, none became infected with the virus 10 to 84 days after vaccination. That’s 100 percent protection, researchers report online December 22 in the Lancet.

    World Health Organization researcher Ana Maria Henao-Restrepo and...

    12/22/2016 - 18:30 Clinical Trials, Health
  • News

    Liberia’s Ebola outbreak largely traced to one source

    A single introduction of the Ebola virus led to most cases of the deadly disease in Liberia, a new genetic study suggests.

    Researchers examined 165 Ebola genomes, most collected during the second wave of infection that started in late May 2014 in the West African country. The analysis, reported online December 9 in Cell Host & Microbe, adds missing information about how the virus...

    12/09/2015 - 12:00 Genetics, Microbiology, Health
  • Science Ticker

    First known case of sexually transmitted Ebola reported

    A Liberian woman contracted Ebola in March by having sex with a survivor of the viral disease, researchers report. Using studies of both people’s viral genomes and of the people’s contacts with any other possible sources of the virus, the researchers conclude that the woman’s disease represents the first known case of sexual transmission of Ebola.

    People ordinarily catch the often-deadly...

    10/14/2015 - 17:00 Health
  • Science Ticker

    New cases of Ebola emerge in Liberia

    Ebola is back in Liberia more than a month after the country thought it was rid of the virus.

    A 17-year-old man died on June 29 of a fever illness that was being treated as malaria. As part of Liberia’s Ebola surveillance, swabs from the young man were collected by a safe burial team. Tests revealed that the young man died of Ebola, the World Health Organization (WHO) announced July 3....

    07/07/2015 - 15:43 Health, Microbiology
  • News

    Ebola continues to shift, but grows no more fatal

    Ebola is evolving, but not becoming deadlier.   

    As it spread internationally in the West African outbreak, the virus changed, but did not become more contagious or lethal, studies published online June 17 in Nature and in the June 18 Cell suggest.

    Researchers analyzed the genetic blueprints of Ebola viruses in hundreds of blood samples from infected patients, comparing these data...

    06/18/2015 - 12:00 Genetics
  • How Bizarre

    An antidepressant may protect against Ebola

    The fearsome Ebola virus may itself fall victim to two already approved medications — the antidepressant drug Zoloft and a drug for patients with heart problems.

    Researchers tested roughly 2,600 compounds and found 30 approved drugs with some capacity to fight the virus in lab-dish tests. The team tested several of these drugs in mice and found that Zoloft, also called sertraline,and the...

    06/03/2015 - 14:00 Biomedicine
  • News in Brief

    Ebola virus not mutating as quickly as thought

    The virus causing the current Ebola epidemic in West Africa is not evolving as quickly as some scientists had suggested.

    In a paper last August, researchers reported that the virus (Zaire ebolavirus) was altering its genes almost twice as fast as it had during previous Ebola outbreaks in Central Africa (SN: 9/20/14, p. 7). However, a new genetic analysis shows that the virus is mutating...

    03/26/2015 - 14:22 Genetics
  • News in Brief

    Ebola virus evolution tracked by genetic data

    SAN JOSE, Calif. — Genetic data are beginning to reveal how the Ebola virus causing the epidemic in Western Africa is evolving.

    Scientists have deciphered the entire catalog of genetic data for 96 Ebola viruses taken from patients infected between June and September 2014. The results show that one particular clade, or type of the virus, is dominant among patients in Sierra Leone,...

    02/14/2015 - 17:00 Genetics, Immune Science, Health
  • Science Ticker

    Ebola vaccine performs well in U.K. human trial

    An Ebola vaccine candidate developed by GlaxoSmithKline and the National Institutes of Health effectively jump-starts the immune system with few side effects, researchers report January 28 in the New England Journal of Medicine.

    The vaccine is based on a chimpanzee cold virus, called adenovirus 3 (ChAd3), that’s been engineered to produce a viral protein specific to the Zaire Ebolavirus...

    01/28/2015 - 17:28 Clinical Trials, Health, Immune Science