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Gonorrhea is a wily foe. But doctors may soon have another drug to fight the sexually transmitted infection that’s become resistant to nearly every antibiotic thrown its way. In clinical trials, a new antibiotic was effective at stopping the bacteria that causes the disease.

A single oral dose of the drug, called zoliflodacin, cured 96 percent of people who had gonorrhea infections in...

For years, scientists have struggled to find a therapy that works for most cystic fibrosis sufferers. Now, two new triple-drug approaches, still undergoing testing, are offering hope.

Cystic fibrosis is caused by mutations in a gene called CFTR. These mutations mean the body either makes defective versions of a protein, also called CFTR, or none of the protein at all. The new therapies...

A daily dose of aspirin? Not a good idea if you’re a healthy elderly adult.

A trio of papers based on a large-scale clinical trial finds that the drug doesn’t help to stave off heart attacks, strokes, dementia or physical disability. In fact, those in their golden years who took a low dose of aspirin daily were more likely to suffer serious internal bleeding than those who took a placebo...

A Nobel Prize–winning discovery — that small double-stranded RNA molecules can silence genes by interrupting the translation of DNA’s instructions into proteins — is finally delivering on its medical promise.

The first drug that takes advantage of this natural biological process, called RNA interference, was approved August 10 by the U.S. Food and Drug Administration. It targets a rare...