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Your search has returned 88 articles:
  • News

    Popular painkiller doesn’t have more heart risks than others, study claims

    NEW ORLEANS — A long-awaited study on painkillers called nonsteroidal anti-inflammatory drugs, the most widely prescribed class of drugs in the world, has concluded that the three most commonly used carry a similar risk of cardiovascular complications. Yet critics say the study was too flawed to fairly compare them.

    Concerns about a type of NSAID called COX-2 inhibitors peaked in 2004...

    11/13/2016 - 21:01 Clinical Trials, Health
  • Feature

    Vaccines could counter addictive opioids

    By age 25, Patrick Schnur had cycled through a series of treatment programs, trying different medications to kick his heroin habit. But the drugs posed problems too: Vivitrol injections were painful and created intense heroin cravings as the drug wore off. Suboxone left him drowsy, depressed and unable to study or go running like he wanted to. Determined to resume the life he had before his...

    06/28/2016 - 12:00 Health, Neuroscience, Clinical Trials
  • Feature

    Vaccines may offer defense against dengue, Zika and chikungunya

    Humans can’t easily protect themselves from the most dangerous species on Earth. The predator slips invisibly into homes, quietly stalks its prey and bites before a victim knows what happened. There’s little chance of escape.

    The attacker is Aedes aegypti, a mosquito that has, over time, developed a taste for people. It’s a city dweller that hovers in undisturbed crannies and can breed...

    06/15/2016 - 08:00 Immune Science, Health, Clinical Trials
  • Science Stats

    There’s more than one way to quit smoking

    For people trying to stop smoking, the how might not really matter.

    Six months after quitting, only about one in four people still abstained from smoking — regardless of whether they used a nicotine patch, twice daily varenicline (a pill that cuts cravings) or a combo nicotine lozenge and patch to quit, researchers report in the Jan. 26 JAMA.

    The study’s authors randomly split 1,...

    02/24/2016 - 07:00 Health, Clinical Trials
  • News in Brief

    Vaginal ring somewhat effective at preventing HIV infection

    A vaginal ring infused with an antiviral drug appears to offer protection against HIV infection, although not as much as doctors had predicted. Women who used the ring had a 27 percent lower risk of HIV infection than women who received a placebo, scientists reported February 22 in the New England Journal of Medicine. A second separate study had similar results, finding a 31 percent reduction...

    02/22/2016 - 15:40 Health, Clinical Trials
  • Science Ticker

    Drug candidate fails to improve symptoms of fragile X syndrome

    An experimental drug for the genetic disorder fragile X syndrome has proven ineffective in two studies in people.

    The syndrome, which is caused by a mutation on the X chromosome, can cause intellectual disability, attention deficit disorder and autism spectrum disorders.

    The drug candidate, called mavoglurant, had shown promise in mice with a genetic condition similar to fragile X...

    01/13/2016 - 14:00 Genetics, Clinical Trials
  • News in Brief

    Drug candidate fails to improve symptoms of fragile X syndrome

    An experimental drug for the genetic disorder fragile X syndrome was ineffective in two studies in people.

    The syndrome, which is caused by a mutation on the X chromosome, can cause intellectual disability, attention deficit disorder and autism spectrum disorders.

    The drug candidate, called mavoglurant, had shown promise in mice with a genetic condition similar to fragile X. The...

    01/13/2016 - 14:00 Genetics, Clinical Trials
  • News

    Dropping blood pressure to 120 lowers heart woes, data confirm

    Aggressive treatment for high blood pressure saves lives, newly released data from a recently halted clinical trial suggests.

    Using drugs to lower systolic blood pressure to less than 120 millimeters of mercury cut people’s risk of heart attacks and other cardiovascular woes by 25 percent, researchers report November 9 in the New England Journal of Medicine. That’s compared with...

    11/09/2015 - 14:16 Clinical Trials, Health
  • News

    Antibodies to fight Alzheimer’s may have unexpected consequences

    In an unexpected twist, two antibodies designed to fight Alzheimer’s disease instead made nerve cells in mice misbehave more.

    The results, published online November 9 in Nature Neuroscience, highlight how little is known about how these drugs actually work, says study coauthor Marc Aurel Busche of Technical University Munich. “We need to understand what these antibodies do in the brains...

    11/09/2015 - 11:00 Health, Clinical Trials, Neuroscience
  • News

    Daily drug shown effective in preventing HIV infections

    After a decade of controversy and halting progress, preexposure prophylaxis may finally be about to take its place in the vanguard of AIDS prevention. 

    In September, for the first time, the World Health Organization expanded the population recommended for this option, which involves taking daily doses of antiviral medication. If a person is exposed to HIV, the drugs should defeat the...

    10/27/2015 - 11:00 Health, Biomedicine, Clinical Trials