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E.g., 11/19/2018
E.g., 11/19/2018
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  • mouse pup
  • mouse embryo developing
  • Lisa Manning
Your search has returned 59 articles:
  • News

    Gene editing creates mice with two biological dads for the first time

    For the first time, researchers have created mice with two dads. No female contributed to the rodents’ genetic makeup.

    This unusual reproduction took place in a lab where researchers gathered fathers’ stem cells, and used them to produce embryos that were implanted into surrogate mothers. The technique required scientists to edit the animals’ genes in order for the mice to mature enough...

    10/11/2018 - 12:02 Cells, Development
  • Science Visualized

    See these dazzling images of a growing mouse embryo

    A new microscope is giving researchers an unprecedented view of how mammals are built, cell by cell.

    Light sheet microscopes use ultrathin laser beams to illuminate sections of a specimen while cameras record those lit-up sections. Previous iterations of the device have captured detailed portraits of living zebra fish and fruit fly embryos as they develop. Kate McDole, a developmental...

    10/11/2018 - 11:00 Cells, Development, Animals
  • Feature

    Lisa Manning describes the physics of how cells move

    Lisa Manning, 38Physics and biologySyracuse University

    Think of tissues as mosh pits of cells. The cells may not be able to crowd surf, but they can jam.

    Specifically, cells can undergo a jamming transition, a physical role change that was previously known to occur only among foams, sand and other nonliving materials. It’s one of the ways that physicist Lisa Manning has shown how...

    09/26/2018 - 08:30 Biomedicine, Cells, Development, Physics
  • News

    Teens born from assisted pregnancies may have higher blood pressure

    Assisted pregnancies give infertile couples the chance at a child. But kids conceived with reproductive technologies, such as in vitro fertilization, or IVF, were more likely to develop high blood pressure as adolescents than their naturally conceived counterparts, a new study finds.  

    Of 52 teens conceived with technological help, eight had hypertension, defined as blood pressure...

    09/05/2018 - 06:00 Health, Development, Epigenetics
  • Mystery Solved

    How salamanders can regrow nearly complete tails but lizards can’t

    Salamanders and lizards can both regrow their tails, but not to equal perfection.

    While a regenerated salamander tail closely mimics the original, bone and all, a lizard’s replacement is filled with cartilage and lacks nerve cells. That contrast is due to differences between stem cells in the animals’ spinal cords, researchers report online August 13 in Proceedings of the National...

    08/17/2018 - 12:30 Cells, Development, Animals, Evolution
  • News in Brief

    Here’s how fast cell death can strike

    Scientists now know how long it takes for a cell to tell itself it’s time to die.

    Signals triggering a type of cell suicide called apoptosis move through a cell like a wave, traveling at a rate of 30 micrometers per minute, Stanford University systems biologists Xianrui Cheng and James Ferrell Jr. report in the Aug. 10 Science.

    These findings resolve a debate over whether these...

    08/09/2018 - 15:17 Cells, Development
  • News

    Zika may harm nearly 1 in 7 babies exposed to the virus in the womb

    Babies exposed to a Zika infection while in the womb are not out of the woods even if they look healthy at birth.

    Nearly 1 in 10 of 1,450 babies examined developed neurological or developmental problems, such as seizures, hearing loss, impaired vision or difficulty crawling, a study from the U.S. Centers for Disease Control and Prevention finds. It’s the first tally of the health of...

    08/07/2018 - 17:27 Health, Development
  • News

    This ‘junk’ gene may be important in embryo development

    A once-maligned genetic parasite may actually be essential for survival.

    Mouse embryos need that genetic freeloader — a type of jumping gene, or transposon, called LINE-1 — to continue developing past the two-cell stage, researchers report in the July 7 Cell.

    Many scientists “charge that these are nasty, selfish genetic elements” that jump around the genome, making mutations and...

    07/03/2018 - 07:00 Development, Cells, Genetics
  • News

    There’s a genetic explanation for why warmer nests turn turtles female

    Toastier nest temperatures, rather than sex chromosomes, turn baby turtles female. Now, a genetic explanation for how temperature determines turtles’ sex is emerging: Scientists have identified a temperature-responsive gene that sets turtle embryos on a path to being either male or female. When researchers dialed down that gene early in development, turtle embryos incubating at the cooler...

    05/10/2018 - 14:00 Development, Genetics
  • News

    A key virus fighter is implicated in pregnancy woes

    An immune system mainstay in the fight against viruses may harm rather than help a pregnancy. In Zika-infected mice, this betrayal appears to contribute to fetal abnormalities  linked to the virus, researchers report online January 5 in Science Immunology. And it could explain pregnancy complications that arise from infections with other pathogens and from autoimmune disorders.

    In...

    01/05/2018 - 15:41 Development, Immune Science