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Biomedicine

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mouse muscle fibers

PUMP IT UP  A new type of CRISPR/Cas9-based gene therapy turned on muscle-building genes in mice that have muscular dystrophy. Muscle fibers (magenta) from mice that got the therapy (right) were bigger than fibers from untreated animals (left).

graphic of an evidence hierarchy

Evidence hierarchies, one version shown, classify types of studies according to the strength of evidence they provide. But a recent paper challenges the assumptions behind these hierarchies.

skin

SKIN REPAIR A 7-year-old with a rare genetic condition lost most of the top layer of his skin, the epidermis. Scientists used a combination of stem cells and gene therapy to repair the damage.  

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