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A new microscopy technique called nonlinear SIM gives a better look at how the cell’s internal scaffolding, or cytoskeleton, changes over time. Shown is a still image from a video of cytoskeletal proteins in a mouse embryonic fibroblast cell. 

CHEMICAL COCKTAIL  Adult skin cells begin to transform into neurons (blue circles with colorful tendrils) just a week after being dosed with seven small-molecule drugs.

microscope image of stem cells in liver

Stem cells, shown here in mouse cells colored red and green, around the central vein of the liver give rise to progeny (in green). 

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