Genes & Cells

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poliovirus

CHANGING FACE  An immunodeficient man has been excreting live poliovirus for 28 years. His viral strains differ from the one he received in a vaccine. A simulated virus particle shows some of these changes, in surface regions (red) that interact with human immune proteins and elsewhere (blue).   

photograph of miniature crime scene by Frances Glessner Lee

CSI: SCIENCE  From fingerprints to blood splatters to DNA, people leave all sorts of traces at the scene of a crime. To help identify suspects, scientists are beefing up classic forensic techniques, and coming up with new ones. One day, microbes and odors from a suspect’s body may give investigators additional pieces of evidence to examine.

illustration of DNA coiled in a sphere

THE SHIFTING NUCLEAR TERRAIN  Within the nucleus, as in this artist’s rendering, the genome coils around proteins and packs into a cell-specific architecture.

Genes & Cells

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