Neuroscience

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 chemical DHED

TARGETED EFFECT  The chemical DHED produces the hormone estrogen in the brain, but not the body. In mice with tissues genetically modified to light up when exposed to estrogen, pure estrogen produces a bright glowing around the internal organs (center). But mice given DHED (left) do not light up more than untreated mice (right), indicating that DHED does not become estrogen in their bodies. 

amoebas (yellow); brain (blood vessel and blood cells shown in blue and orange)

BRAIN BOUND  Naegleria fowleri amoebas (yellow) get into the brain through the nose and attack tissue in the brain (blood vessel and blood cells shown in blue and orange), but the major danger comes from the immune system’s reaction, scientists suggest.

Brainlike structures

STOP SIGNS  Brainlike structures grown from autistic patients’ stem cells (right) produced greater numbers of brain cells that make other brain cells less active (green and red) compared with structures grown from the cells of a non-autistic family member (left). These cells were observed 31 days after the stem cells became brain cells. 

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