With influenza vaccine, bigger may be better
Compared with standard vaccination, a beefed-up flu shot better protects older adults against the virus, researchers report in the Aug. 14 New England Journal of Medicine.
The elderly are at higher risk of flu because immunity wanes with age, and aging decreases the body's ability to take full advantage of a vaccination. In 2009, a “high-dose” flu shot for people age 65 and older was approved. While the vaccine boosts the immune response, it had been unclear whether that translated into fewer cases of the flu.