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Growth hormone's risks outweigh its benefits

From Boston, at a meeting of the Endocrine Society

Human growth hormone has substantial risks and no functional benefits for healthy, elderly people, according to a comprehensive review.

Injections of the substance are an approved therapy in children and adults who have growth-hormone deficiency, a defect that can lead to short stature and other health problems. It's a valuable medicine for those individuals, says Hau Liu of Stanford University.

But an estimated 30,000 generally healthy people in the United States, mostly elderly adults, take the hormone for its putative antiaging effects. Various organizations that promote growth hormone for this purpose often cite a 1990 research finding that growth hormone promotes fat loss, muscle-mass increase, and maintenance of healthy skin.

"Based on the evidence we reviewed, which includes the evidence [from 1990], we do not recommend growth hormone for antiaging," Liu says.

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